The human heart is an incredibly sophisticated organ that, in addition to being one of the first organs developed while embryos develop, is quite difficult to understand at a cellular level (where are the cells, how do they first develop, etc.).
Neil Chi’s group at UCSD (link to Nature paper) were able to use multiplex imaging of fluorescent-tagged RNA molecules to profile the gene expression profiles of different types of heart cells and see where they are located and how they develop!
The result is an amazing visualization, check it out at the video:
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